half light

We had sun yesterday! But mostly, we have had rain rain rain and clouds on the Olympic Peninsula this spring.

With record breaking temperatures across the US, I can’t complain much about rain. I took today’s photograph a few days ago, in the early morning. We walk hoping the sun will peek through. It is peeking through but not on us. It is peeking far over the water in the distance.

For the Ragtag Daily Prompt: half light.

colossal

The hills don’t look that colossal, do they? But this is taken zoomed in from the Olympic Peninsula and the hills are on Vancouver Island. Here is one not zoomed:

It was a colossally low tide and we were hunting fossils. Fossil clams, fossil snails and stories of fossil dinosaur bones.

For the Ragtag Daily Prompt: colossal.

before the rain

I took this two days ago on an early beach walk starting at North Beach. The sky was amazing and beautiful. We had intermittent sun through the clouds and very little rain on that walk. It’s easier to see the clear agates when the sun lights them up.

I did not find any clear agates. B found one that met his criteria. There were many other beautiful rocks. This one was way too big to bring home. The rock itself is almost a rainbow.

For the Ragtag Daily Prompt: rainbow.

Volume of water

We check the tides before we go walk the beaches on the Olympic Peninsula. I am learning the patterns of the tide locally. On North Beach, the tide is about an hour later each day. However, low tide is at a different time further out the Olympic Peninsula. I had to think about that a bit.

Picture the tide a low with the Salish Sea volume down. Then the tide turns and starts flowing back in. The Salish Sea is like the roots of a tree, with a main trunk and then branches and branches and more branches. There is water coming in from the land, from streams and from rivers, but the tide rolls in from the trunk first and then spreads through all of the roots. I have a tide table for the peninsula for this year, and it has tables for multiple different sites! Most days we have two high and two low tides, but once in a while the low goes out so little that it matches both highs, and we only have two tides that day, a high and a low!

I took the photograph at Dungeness Spit this month. The tide was nearly low when we started walking and we only went 2-3 miles down the spit and turned back. It is beautiful! Check the weather, check the tides and always take something rain proof, even in July. Our water is not warm.

For the Ragtag Daily Prompt: volume.

Bird talk

A photo tale from a hike last week.

Her: “I think we should discuss our future.”

Him: “Well, um.”

Her: “Wait. Are you trying to tell me something?”

Her: “Is there someone else!!?!”

Him: “I was going to tell you!”

Her: “You lying scum.”

Him: “Wait! Oh, no, she’s GONE.”

__________________________________

For the Ragtag Daily Prompt: create.

These are Pigeon Guillemots, more here.

Photographs taken on Marrowstone Island last week.

behavioral health, cancer, and the immune system

There are more and more articles about immune causes of “behavioral health” diagnoses.

The latest I’ve read is about schizophrenia:

https://www.nature.com/articles/s41598-020-63776-0

Auto-antibodies are antibodies that we make against something else that then attack a part of ourselves. The most well know version of an auto-antibody is Rheumatic Fever, where an antibody to streptococcus A attacks the joints or skin or heart. I had a patient in Colorado who needed a new heart valve at age 10 or 11 because of Rheumatic Fever.

I have written a lot about PANDAS and PANS (respectively Pediatric Autoimmune Neuropsychiatric Disorders Associated with Strep A and Pediatric Acute Neuropsychiatric Syndrome) because an older psychiatrist was suspicious that I have PANS. I have had pneumonia four times and it is accompanied by anxiety and fear, part of which turns out to be hypoxia and tachycardia. I think a heart rate of 135 makes just about ANYONE feel anxious. It feels awful.

But what about other Behavioral Health Diagnoses? Remember, we are on the DSM V, the fifth manual of psychiatric diagnoses. We have not had markers or a clear cause. That is, we are aware that serotonin is low in the intracellular spaces in the brain with depression but we don’t know what the mechanism is, what the cause is and what exactly is happening in the neuron or brain cells. A paper on a particular rat neuron said that there were 300 different types of serotonin receptors on that neuron. Blocking one type caused rats to act in an obsessive compulsive manner. But there are 299 others and then combinations. Whew, there is a lot to be learned about the brain.

Fibromyalgia can be caused by autoantibodies, at least some of the cases: https://www.sciencedaily.com/releases/2021/07/210701120703.htm

Chronic fatigue: https://pubmed.ncbi.nlm.nih.gov/34441971/

Lupus and fibromyalgia overlap: https://pubmed.ncbi.nlm.nih.gov/9207710/

Autoimmune disorders are more common in women. We think this is because of pregnancy. The woman’s immune system has to tolerate a pregnancy where half the genetic material is from the father. Yet the immune system also has to recognize “not me, infection” and be able to distinguish that from the pregnancy. This is tricky. The most common autoimmune disorder currently is believed to be Hashimoto’s Thyroiditis, where there are self antibodies to the thyroid. Post covid could potentially beat this out.

Chronic fatigue and fibromyalgia have been orphan diseases in that we do not have an inflammation marker that defines them. The ESR (erythrocyte sedimentation rate) and CRP (um) are usually normal. These are often elevated in rheumatological disorders. Not having a marker doesn’t mean that the muscles are not painful and doesn’t mean that the fatigue is not real.

I am hopeful that we are on the cusp of a true revolution in medicine, with more understanding of the immune system and behavioral health disorders, as well as post covid, fibromyalgia and chronic fatigue. I worked at the National Cancer Institute in the 1980s before medical school, with Steve Rosenberg, MD. He was trying to get the immune system to fight cancer.

Now there has been a cancer treatment with 100% success: an immune treatment for people with rectal cancer with a particular immune profile. This is AMAZING! https://www.zmescience.com/science/experimental-trial-cancer-complete-remission-02725735/

Only 18 patients, but 100% success! No surgery.

The patch for the National Cancer Institute shows a man fighting a crab: Cancer, the crab. Dr. Rosenberg talked about Sysiphus, who was rolling a stone up a mountain eternally while it rolled back on him. From here: Later legend related that when Death came to fetch him, Sisyphus chained Death up so that no one died. Finally, Ares came to aid Death, and Sisyphus had to submit. In the meantime, Sisyphus had told his wife, Merope, not to perform the usual sacrifices and to leave his body unburied. Thus, when he reached the underworld, he was permitted to return to punish her for the omission. Once back at home, Sisyphus continued to live to a ripe old age before dying a second time.

Maybe the stone has reached a resting place. Blessings and peace you. Please peace me.

path

This is normally a path by the Kai Tai Lagoon. However, we had a very heavy rain and the water backed up into the Safeway parking lot. Here is the gulch where it is running into Kai Tai Lagoon:

The parking lot had drained when I walked down 14th Street, but the ducks were investigating the ditches as very attractive small ponds.

There was still a lot of water. The ditches were ponds.

We have businesses in the underground downtown and at least some of them were flooded. And we are expecting another atmospheric river in the sky this weekend.

The last picture is in Maryland, amazing clouds.

For the Ragtag Daily Prompt: gulch.